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W Lindsley

Showing results (361-370 of 570) with videos related to

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Advances in Therapy|May 27, 2024
Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma Across Multiple Clinically Relevant Subgroups in the NAVIGATOR StudyTara F Carr, Wendy C Moore, Monica Kraft, et al.
Biorxiv : the Preprint Server for Biology|February 20, 2025
Cryo-EM reveals a new allosteric binding site at the M<sub>5</sub> mAChRWessel A C Burger, Jesse I Mobbs, Bhavika Rana, et al.
ACS Chemical Biology|April 20, 2021
Ten-Year Retrospective of the Vanderbilt Institute of Chemical Biology Chemical Synthesis CoreKwangho Kim, Plamen P Christov, Ian Romaine, et al.
Nature Communications|July 31, 2025
Cryo-EM reveals an extrahelical allosteric binding site at the M<sub>5</sub> mAChRWessel A C Burger, Jesse I Mobbs, Bhavika Rana, et al.
Bioorganic & Medicinal Chemistry Letters|December 3, 2019
Discovery of structurally distinct tricyclic M<sub>4</sub> positive allosteric modulator (PAM) chemotypesKayla J Temple, Madeline F Long, Julie L Engers, et al.
Bioorganic & Medicinal Chemistry Letters|January 28, 2014
Novel GlyT1 inhibitor chemotypes by scaffold hopping. Part 2: development of a [3.3.0]-based series and other piperidine bioisosteresDouglas J Sheffler, Michael T Nedelcovych, Richard Williams, et al.
Bioorganic & Medicinal Chemistry Letters|October 16, 2012
Synthesis and biological characterization of a series of novel diaryl amide M₁ antagonistsMichael S Poslusney, Christian Sevel, Thomas J Utley, et al.
ACS Medicinal Chemistry Letters|September 17, 2025
Characterization of Next-Generation Inhibitors for the Inward-Rectifier Potassium Channel K<sub>ir</sub>2.1: Discovery of VU6080824Renn A Duncan, Daniel H Haymer, Roman M Lazarenko, et al.
Bioorganic & Medicinal Chemistry Letters|February 8, 2021
Discovery and optimization of a novel CNS penetrant series of mGlu<sub>4</sub> PAMs based on a 1,4-thiazepane core with in vivo efficacy in a preclinical Parkinsonian modelCaitlin N Kent, Mark G Fulton, Kaylee J Stillwell, et al.
Molecular Pharmacology|August 16, 2003
A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5Julie A O'Brien, Wei Lemaire, Tsing-Bau Chen, et al.
Pageof 57

Showing results (361-370 of 570) with videos related to

Sort By:
Pageof 57
Advances in Therapy|May 27, 2024
Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma Across Multiple Clinically Relevant Subgroups in the NAVIGATOR StudyTara F Carr, Wendy C Moore, Monica Kraft, et al.
Biorxiv : the Preprint Server for Biology|February 20, 2025
Cryo-EM reveals a new allosteric binding site at the M<sub>5</sub> mAChRWessel A C Burger, Jesse I Mobbs, Bhavika Rana, et al.
ACS Chemical Biology|April 20, 2021
Ten-Year Retrospective of the Vanderbilt Institute of Chemical Biology Chemical Synthesis CoreKwangho Kim, Plamen P Christov, Ian Romaine, et al.
Nature Communications|July 31, 2025
Cryo-EM reveals an extrahelical allosteric binding site at the M<sub>5</sub> mAChRWessel A C Burger, Jesse I Mobbs, Bhavika Rana, et al.
Bioorganic & Medicinal Chemistry Letters|December 3, 2019
Discovery of structurally distinct tricyclic M<sub>4</sub> positive allosteric modulator (PAM) chemotypesKayla J Temple, Madeline F Long, Julie L Engers, et al.
Bioorganic & Medicinal Chemistry Letters|January 28, 2014
Novel GlyT1 inhibitor chemotypes by scaffold hopping. Part 2: development of a [3.3.0]-based series and other piperidine bioisosteresDouglas J Sheffler, Michael T Nedelcovych, Richard Williams, et al.
Bioorganic & Medicinal Chemistry Letters|October 16, 2012
Synthesis and biological characterization of a series of novel diaryl amide M₁ antagonistsMichael S Poslusney, Christian Sevel, Thomas J Utley, et al.
ACS Medicinal Chemistry Letters|September 17, 2025
Characterization of Next-Generation Inhibitors for the Inward-Rectifier Potassium Channel K<sub>ir</sub>2.1: Discovery of VU6080824Renn A Duncan, Daniel H Haymer, Roman M Lazarenko, et al.
Bioorganic & Medicinal Chemistry Letters|February 8, 2021
Discovery and optimization of a novel CNS penetrant series of mGlu<sub>4</sub> PAMs based on a 1,4-thiazepane core with in vivo efficacy in a preclinical Parkinsonian modelCaitlin N Kent, Mark G Fulton, Kaylee J Stillwell, et al.
Molecular Pharmacology|August 16, 2003
A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5Julie A O'Brien, Wei Lemaire, Tsing-Bau Chen, et al.
Pageof 57