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Nature
|
July 13, 2022
Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex
Jason J Kwon, Behnoush Hajian, Yuemin Bian, et al.
ACS Medicinal Chemistry Letters
|
February 16, 2013
Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor that Affords Robust CNS Aβ Reduction
Andrew W Stamford, Jack D Scott, Sarah W Li, et al.
Journal of Medicinal Chemistry
|
December 10, 2016
Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)-A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer's Disease
Jack D Scott, Sarah W Li, Andrew P J Brunskill, et al.
Cancer Discovery
|
September 2, 2022
Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia
Yiman Liu, Qinglan Li, Fatemeh Alikarami, et al.
Biorxiv : the Preprint Server for Biology
|
November 14, 2023
Recruitment of FBXO22 for Targeted Degradation of NSD2
David Y Nie, John R Tabor, Jianping Li, et al.
Nature Chemical Biology
|
July 4, 2024
Recruitment of FBXO22 for targeted degradation of NSD2
David Y Nie, John R Tabor, Jianping Li, et al.
Journal of Medicinal Chemistry
|
March 4, 2016
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors
Christopher J Bungard, Peter D Williams, Jurgen Schulz, et al.
Journal of Medicinal Chemistry
|
March 1, 2017
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
Jack D Scott, Duane E DeMong, Thomas J Greshock, et al.
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Showing results (31-40 of 39) with videos related to
Sort By:
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You have reached the last page of results.
This site can display upto 39 results.
Nature
|
July 13, 2022
Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex
Jason J Kwon, Behnoush Hajian, Yuemin Bian, et al.
ACS Medicinal Chemistry Letters
|
February 16, 2013
Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor that Affords Robust CNS Aβ Reduction
Andrew W Stamford, Jack D Scott, Sarah W Li, et al.
Journal of Medicinal Chemistry
|
December 10, 2016
Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)-A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer's Disease
Jack D Scott, Sarah W Li, Andrew P J Brunskill, et al.
Cancer Discovery
|
September 2, 2022
Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia
Yiman Liu, Qinglan Li, Fatemeh Alikarami, et al.
Biorxiv : the Preprint Server for Biology
|
November 14, 2023
Recruitment of FBXO22 for Targeted Degradation of NSD2
David Y Nie, John R Tabor, Jianping Li, et al.
Nature Chemical Biology
|
July 4, 2024
Recruitment of FBXO22 for targeted degradation of NSD2
David Y Nie, John R Tabor, Jianping Li, et al.
Journal of Medicinal Chemistry
|
March 4, 2016
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors
Christopher J Bungard, Peter D Williams, Jurgen Schulz, et al.
Journal of Medicinal Chemistry
|
March 1, 2017
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
Jack D Scott, Duane E DeMong, Thomas J Greshock, et al.
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