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Journal of Neuroscience Research|November 5, 2003
Identity and function of gamma-secretaseW Taylor Kimberly, Michael S WolfeProceedings of the National Academy of Sciences of the United States of America|May 13, 2003
Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2W Taylor Kimberly, Matthew J LaVoie, Beth L Ostaszewski, et al.The Journal of Biological Chemistry|July 20, 2002
Complex N-linked glycosylated nicastrin associates with active gamma-secretase and undergoes tight cellular regulationW Taylor Kimberly, Matthew J LaVoie, Beth L Ostaszewski, et al.Neurobiology of Disease|October 24, 2003
Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substratesStephanie Baulac, Matthew J LaVoie, W Taylor Kimberly, et al.The Journal of Biological Chemistry|July 15, 2003
Assembly of the gamma-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrinMatthew J LaVoie, Patrick C Fraering, Beth L Ostaszewski, et al.Proceedings of the National Academy of Sciences of the United States of America|February 28, 2002
Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrateWilliam P Esler, W Taylor Kimberly, Beth L Ostaszewski, et al.Biochemistry|January 14, 2004
Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complexPatrick C Fraering, Matthew J LaVoie, Wenjuan Ye, et al.Biochemistry|January 8, 2003
Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s)W Taylor Kimberly, William P Esler, Wenjuan Ye, et al.Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics|November 23, 2011
Biomarkers in neurocritical careW Taylor KimberlyFASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|November 9, 2002
Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in DrosophilaCraig A Micchelli, William P Esler, W Taylor Kimberly, et al.Pageof 31