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Organic Letters
|
June 7, 2002
A convergent synthesis of the tricyclic architecture of the guanacastepenes featuring a selective ring fragmentation
William D Shipe, Erik J Sorensen
Journal of the American Chemical Society
|
May 25, 2006
Convergent, enantioselective syntheses of guanacastepenes A and E featuring a selective cyclobutane fragmentation
William D Shipe, Erik J Sorensen
Drug Discovery Today. Technologies
|
July 2, 2014
Accelerating lead development by microwave-enhanced medicinal chemistry
William D Shipe, Scott E Wolkenberg, Craig W Lindsley
Current Opinion in Drug Discovery & Development
|
July 19, 2005
Recent advances in positive allosteric modulators of metabotropic glutamate receptors
William D Shipe, Scott E Wolkenberg, David L Williams, et al.
Current Opinion in Drug Discovery & Development
|
November 30, 2005
Applications of microwave-assisted organic synthesis on the multigram scale
Scott E Wolkenberg, William D Shipe, Craig W Lindsley, et al.
Current Topics in Medicinal Chemistry
|
May 25, 2006
Progress towards validating the NMDA receptor hypofunction hypothesis of schizophrenia
Craig W Lindsley, William D Shipe, Scott E Wolkenberg, et al.
Journal of Medicinal Chemistry
|
September 18, 2015
Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel Synthesis
William D Shipe, Steven S Sharik, James C Barrow, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 17, 2009
Parallel synthesis of N-biaryl quinolone carboxylic acids as selective M(1) positive allosteric modulators
Feng V Yang, William D Shipe, Jaime L Bunda, et al.
Journal of Medicinal Chemistry
|
April 19, 2017
Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles
John M Sanders, Douglas C Beshore, J Christopher Culberson, et al.
Journal of Medicinal Chemistry
|
January 10, 2023
Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia
Mark E Layton, Jeffrey C Kern, Timothy J Hartingh, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 17) with videos related to
Sort By:
Page
of 2
Organic Letters
|
June 7, 2002
A convergent synthesis of the tricyclic architecture of the guanacastepenes featuring a selective ring fragmentation
William D Shipe, Erik J Sorensen
Journal of the American Chemical Society
|
May 25, 2006
Convergent, enantioselective syntheses of guanacastepenes A and E featuring a selective cyclobutane fragmentation
William D Shipe, Erik J Sorensen
Drug Discovery Today. Technologies
|
July 2, 2014
Accelerating lead development by microwave-enhanced medicinal chemistry
William D Shipe, Scott E Wolkenberg, Craig W Lindsley
Current Opinion in Drug Discovery & Development
|
July 19, 2005
Recent advances in positive allosteric modulators of metabotropic glutamate receptors
William D Shipe, Scott E Wolkenberg, David L Williams, et al.
Current Opinion in Drug Discovery & Development
|
November 30, 2005
Applications of microwave-assisted organic synthesis on the multigram scale
Scott E Wolkenberg, William D Shipe, Craig W Lindsley, et al.
Current Topics in Medicinal Chemistry
|
May 25, 2006
Progress towards validating the NMDA receptor hypofunction hypothesis of schizophrenia
Craig W Lindsley, William D Shipe, Scott E Wolkenberg, et al.
Journal of Medicinal Chemistry
|
September 18, 2015
Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel Synthesis
William D Shipe, Steven S Sharik, James C Barrow, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 17, 2009
Parallel synthesis of N-biaryl quinolone carboxylic acids as selective M(1) positive allosteric modulators
Feng V Yang, William D Shipe, Jaime L Bunda, et al.
Journal of Medicinal Chemistry
|
April 19, 2017
Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles
John M Sanders, Douglas C Beshore, J Christopher Culberson, et al.
Journal of Medicinal Chemistry
|
January 10, 2023
Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia
Mark E Layton, Jeffrey C Kern, Timothy J Hartingh, et al.
Page
of 2