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Bioorganic & Medicinal Chemistry Letters|April 18, 2021
Discovery of a new series of PI3K-δ inhibitors from Virtual ScreeningXavier Fradera, Qiaolin Deng, Abdelganhi Achab, et al.Journal of Medicinal Chemistry|April 21, 2009
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's diseaseJosé Marco-Contelles, Rafael León, Cristóbal de los Ríos, et al.Journal of Medicinal Chemistry|June 23, 2022
Cosolvent Sites-Based Discovery of <i>Mycobacterium Tuberculosis</i> Protein Kinase G InhibitorsOsvaldo Burastero, Lucas A Defelipe, Gabriel Gola, et al.Bioorganic & Medicinal Chemistry Letters|November 24, 2019
Discovery and optimization of heteroaryl piperazines as potent and selective PI3Kδ inhibitorsHua Zhou, Meredeth A McGowan, Kathryn Lipford, et al.Chemmedchem|August 28, 2024
The Role of Water Networks in Phosphodiesterase Inhibitor Dissociation and Kinetic SelectivityAntoni R Blaazer, Abhimanyu K Singh, Lorena Zara, et al.Chembiochem : a European Journal of Chemical Biology|January 5, 2021
Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine MethyltransferaseVladimir O Talibov, Edoardo Fabini, Edward A FitzGerald, et al.ACS Medicinal Chemistry Letters|May 14, 2025
The Discovery of Bridged Benzoazepine Amides as Selective Allosteric Modulators of RIPK1Joanna L Chen, Joey L Methot, Matthew J Mitcheltree, et al.ACS Medicinal Chemistry Letters|September 17, 2021
Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 InhibitorsBrett Hopkins, Hongjun Zhang, Indu Bharathan, et al.ACS Medicinal Chemistry Letters|April 16, 2021
Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool CompoundsBrandon A Vara, Samuel M Levi, Abdelghani Achab, et al.ACS Medicinal Chemistry Letters|August 25, 2020
Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) InhibitorsQinglin Pu, Hongjun Zhang, Liangqin Guo, et al.Pageof 13