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Journal of Medicinal Chemistry
|
September 23, 2024
Use of the Novel Site-Directed Enzyme Enhancement Therapy (SEE-Tx) Drug Discovery Platform to Identify Pharmacological Chaperones for Glutaric Acidemia Type 1
Madalena Barroso, Alexandra Puchwein-Schwepcke, Lars Buettner, et al.
International Journal of Molecular Sciences
|
May 4, 2026
Development of Small-Molecule Allosteric Modulators of Beta-Galactosidase (β-Gal) for the Treatment of GM1 Gangliosidosis and Morquio B
Natàlia Pérez-Carmona, Elena Cubero, Ana Ruano, et al.
Angewandte Chemie (International Ed. in English)
|
November 21, 2025
Water Networks as Hydrophobic Recognition Motifs in Proteins
Serena G Piticchio, Miriam Martínez-Cartró, Salvatore Scaffidi, et al.
Journal of Medicinal Chemistry
|
June 25, 2005
Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design
Brian W Dymock, Xavier Barril, Paul A Brough, et al.
Journal of Medicinal Chemistry
|
December 13, 2021
Discovery of Novel BRD4 Ligand Scaffolds by Automated Navigation of the Fragment Chemical Space
Serena G Piticchio, Míriam Martínez-Cartró, Salvatore Scaffidi, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 17, 2006
4-Amino derivatives of the Hsp90 inhibitor CCT018159
Xavier Barril, Mandy C Beswick, Adam Collier, et al.
Chemmedchem
|
November 11, 2015
Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor
Núria Bayó-Puxan, Ricard Rodríguez-Mias, Michael Goldflam, et al.
Plos One
|
November 29, 2023
Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors
Mikhail Rudinskiy, Maria Pons-Vizcarra, Tatiana Soldà, et al.
Chemical Science
|
June 14, 2021
Fluorogenic Trp(redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas
Ramon Subiros-Funosas, Vivian Cheuk Lam Ho, Nicole D Barth, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|
August 20, 2025
Discovering Uncharted Binding Pockets on E3 Ligases Leads to the Identification of FBW7 Allosteric Modulators
Míriam Martínez-Cartró, Álvaro Serrano-Morrás, Andrea Bertran-Mostazo, et al.
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Search research articles
Search
Showing results (61-70 of 82) with videos related to
Sort By:
Page
of 9
Journal of Medicinal Chemistry
|
September 23, 2024
Use of the Novel Site-Directed Enzyme Enhancement Therapy (SEE-Tx) Drug Discovery Platform to Identify Pharmacological Chaperones for Glutaric Acidemia Type 1
Madalena Barroso, Alexandra Puchwein-Schwepcke, Lars Buettner, et al.
International Journal of Molecular Sciences
|
May 4, 2026
Development of Small-Molecule Allosteric Modulators of Beta-Galactosidase (β-Gal) for the Treatment of GM1 Gangliosidosis and Morquio B
Natàlia Pérez-Carmona, Elena Cubero, Ana Ruano, et al.
Angewandte Chemie (International Ed. in English)
|
November 21, 2025
Water Networks as Hydrophobic Recognition Motifs in Proteins
Serena G Piticchio, Miriam Martínez-Cartró, Salvatore Scaffidi, et al.
Journal of Medicinal Chemistry
|
June 25, 2005
Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design
Brian W Dymock, Xavier Barril, Paul A Brough, et al.
Journal of Medicinal Chemistry
|
December 13, 2021
Discovery of Novel BRD4 Ligand Scaffolds by Automated Navigation of the Fragment Chemical Space
Serena G Piticchio, Míriam Martínez-Cartró, Salvatore Scaffidi, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 17, 2006
4-Amino derivatives of the Hsp90 inhibitor CCT018159
Xavier Barril, Mandy C Beswick, Adam Collier, et al.
Chemmedchem
|
November 11, 2015
Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor
Núria Bayó-Puxan, Ricard Rodríguez-Mias, Michael Goldflam, et al.
Plos One
|
November 29, 2023
Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors
Mikhail Rudinskiy, Maria Pons-Vizcarra, Tatiana Soldà, et al.
Chemical Science
|
June 14, 2021
Fluorogenic Trp(redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas
Ramon Subiros-Funosas, Vivian Cheuk Lam Ho, Nicole D Barth, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|
August 20, 2025
Discovering Uncharted Binding Pockets on E3 Ligases Leads to the Identification of FBW7 Allosteric Modulators
Míriam Martínez-Cartró, Álvaro Serrano-Morrás, Andrea Bertran-Mostazo, et al.
Page
of 9