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Bioorganic & Medicinal Chemistry Letters
|
August 17, 2019
Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow
Xavier Fradera, Joey L Methot, Abdelghani Achab, et al.
ACS Medicinal Chemistry Letters
|
March 19, 2021
Identification of Potent Reverse Indazole Inhibitors for HPK1
Elsie C Yu, Joey L Methot, Xavier Fradera, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2020
Corrigendum to "Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow" [Bioorg. Med. Chem. Lett. 29 (2019) 2575-2580]
Xavier Fradera, Joey L Methot, Abdelghani Achab, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 15, 2021
Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold
Wensheng Yu, Yongqi Deng, David Sloman, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 14, 2011
1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors: separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen pka
Wullie Arbuckle, Mark Baugh, Simone Belshaw, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 18, 2021
Discovery of a new series of PI3K-δ inhibitors from Virtual Screening
Xavier Fradera, Qiaolin Deng, Abdelganhi Achab, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 24, 2019
Discovery and optimization of heteroaryl piperazines as potent and selective PI3Kδ inhibitors
Hua Zhou, Meredeth A McGowan, Kathryn Lipford, et al.
ACS Medicinal Chemistry Letters
|
May 14, 2025
The Discovery of Bridged Benzoazepine Amides as Selective Allosteric Modulators of RIPK1
Joanna L Chen, Joey L Methot, Matthew J Mitcheltree, et al.
ACS Medicinal Chemistry Letters
|
September 17, 2021
Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors
Brett Hopkins, Hongjun Zhang, Indu Bharathan, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2021
Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds
Brandon A Vara, Samuel M Levi, Abdelghani Achab, et al.
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Showing results (21-30 of 49) with videos related to
Sort By:
Page
of 5
Bioorganic & Medicinal Chemistry Letters
|
August 17, 2019
Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow
Xavier Fradera, Joey L Methot, Abdelghani Achab, et al.
ACS Medicinal Chemistry Letters
|
March 19, 2021
Identification of Potent Reverse Indazole Inhibitors for HPK1
Elsie C Yu, Joey L Methot, Xavier Fradera, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2020
Corrigendum to "Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow" [Bioorg. Med. Chem. Lett. 29 (2019) 2575-2580]
Xavier Fradera, Joey L Methot, Abdelghani Achab, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 15, 2021
Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold
Wensheng Yu, Yongqi Deng, David Sloman, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 14, 2011
1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors: separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen pka
Wullie Arbuckle, Mark Baugh, Simone Belshaw, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 18, 2021
Discovery of a new series of PI3K-δ inhibitors from Virtual Screening
Xavier Fradera, Qiaolin Deng, Abdelganhi Achab, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 24, 2019
Discovery and optimization of heteroaryl piperazines as potent and selective PI3Kδ inhibitors
Hua Zhou, Meredeth A McGowan, Kathryn Lipford, et al.
ACS Medicinal Chemistry Letters
|
May 14, 2025
The Discovery of Bridged Benzoazepine Amides as Selective Allosteric Modulators of RIPK1
Joanna L Chen, Joey L Methot, Matthew J Mitcheltree, et al.
ACS Medicinal Chemistry Letters
|
September 17, 2021
Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors
Brett Hopkins, Hongjun Zhang, Indu Bharathan, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2021
Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds
Brandon A Vara, Samuel M Levi, Abdelghani Achab, et al.
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