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Biorxiv : the Preprint Server for Biology|March 30, 2023
Immunogenetic metabolomics revealed key enzymes that modulate CAR-T metabolism and functionPaul Renauer, Jonathan J Park, Meizhu Bai, et al.
Nature Biotechnology|January 26, 2023
Massively parallel knock-in engineering of human T cellsXiaoyun Dai, Jonathan J Park, Yaying Du, et al.
Nature Immunology|October 16, 2019
Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunityGuangchuan Wang, Ryan D Chow, Zhigang Bai, et al.
Oncotarget|January 14, 2017
A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinomaXiaoyun Dai, Lingzhi Wang, Amudha Deivasigamni, et al.
Molecular Oncology|January 28, 2015
Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3Xiaoyun Dai, Kwang Seok Ahn, Chulwon Kim, et al.
Molecular Cancer Therapeutics|October 22, 2016
Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular CarcinomaXiaoyun Dai, Kwang Seok Ahn, Ling Zhi Wang, et al.
Biorxiv : the Preprint Server for Biology|March 30, 2023
Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineeringMatthew B Dong, Kaiyuan Tang, Xiaoyu Zhou, et al.
Cancer Discovery|September 5, 2020
CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint BlockadeGuangchuan Wang, Ryan D Chow, Lvyun Zhu, et al.
The Journal of Biological Chemistry|October 17, 2014
Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivoChakrabhavi Dhananjaya Mohan, Hanumantharayappa Bharathkumar, Krishna C Bulusu, et al.
Cell Metabolism|March 11, 2022
A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapyLupeng Ye, Jonathan J Park, Lei Peng, et al.
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