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Journal of Medicinal Chemistry|October 20, 2025
Structure- and Privileged Fragment-Based Iterative Optimization: Discovery of 2,4-Disubstituted-6-aminopyrimidines as Novel HIV-1 NNRTIs with Potent Activity against Drug-Resistant Strains and Favorable Safety ProfilesXiangkai Ji, Xiangyi Jiang, Heng Gao, et al.
Bioorganic & Medicinal Chemistry|August 24, 2014
Arylazolyl(azinyl)thioacetanilides. Part 16: Structure-based bioisosterism design, synthesis and biological evaluation of novel pyrimidinylthioacetanilides as potent HIV-1 inhibitorsXiao Li, Xueyi Lu, Wenmin Chen, et al.
Pharmaceuticals (Basel, Switzerland)|November 24, 2022
Identification of Novel Diarylpyrimidines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors by Exploring the Primer Grip RegionTao Zhang, Zhongxia Zhou, Fabao Zhao, et al.
Chemical Society Reviews|February 17, 2021
Medicinal chemistry strategies for discovering antivirals effective against drug-resistant virusesYue Ma, Estrella Frutos-Beltrán, Dongwei Kang, et al.
Bioorganic & Medicinal Chemistry|March 18, 2014
Fused heterocyclic compounds bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 1: design, synthesis and biological evaluation of novel 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivativesYe Tian, Deping Du, Diwakar Rai, et al.
Medicinal Chemistry (Shariqah (United Arab Emirates))|March 11, 2014
Design, synthesis and biological evaluation of substituted guanidine indole derivatives as potential inhibitors of HIV-1 Tat-TAR interactionJun Wang, Yan Wang, Zhenyu Li, et al.
Bioorganic & Medicinal Chemistry|October 27, 2012
Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approachPeng Zhan, Wenmin Chen, Zhenyu Li, et al.
Chemical Biology & Drug Design|January 29, 2015
Synthesis and Biological Evaluation of a Series of 2-((1-substituted-1H-1,2,3-triazol-4-yl)methylthio)-6-(naphthalen-1-ylmethyl)pyrimidin-4(3H)-one As Potential HIV-1 InhibitorsZengjun Fang, Dongwei Kang, Lingzi Zhang, et al.
European Journal of Medicinal Chemistry|April 29, 2014
Discovery of novel diarylpyrimidines as potent HIV NNRTIs via a structure-guided core-refining approachXiao Li, Wenmin Chen, Ye Tian, et al.
Expert Opinion on Therapeutic Patents|January 10, 2023
Novel urate transporter 1 (URAT1) inhibitors: a review of recent patent literature (2020-present)Xiaoyu Shi, Tong Zhao, Edeildo Ferreira da Silva-Júnior, et al.
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