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Yichin Liu

Showing results (31-40 of 54) with videos related to

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Mabs|January 31, 2020
Improved translation of stability for conjugated antibodies using an in vitro whole blood assayAimee Fourie-O'Donohue, Phillip Y Chu, Josefa Dela Cruz Chuh, et al.
Journal of Medicinal Chemistry|September 21, 2017
Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's DiseaseSnahel Patel, William J Meilandt, Rebecca I Erickson, et al.
Analytical Chemistry|December 12, 2023
Translatability of <i>In Vitro</i> Stress for Predicting Deamidation and Oxidation Biotransformation on BiotherapeuticsPhillip Y Chu, Hui Wang, Emily Ross, et al.
Journal of Medicinal Chemistry|October 3, 2015
Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N-(1H-Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12)Snahel Patel, Seth F Harris, Paul Gibbons, et al.
Bioorganic & Medicinal Chemistry Letters|August 9, 2016
Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitorsSharada S Labadie, Peter S Dragovich, Richard T Cummings, et al.
Bioorganic & Medicinal Chemistry Letters|September 10, 2013
Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenaseBenjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Bioconjugate Chemistry|February 10, 2018
High-Throughput Cysteine Scanning To Identify Stable Antibody Conjugation Sites for Maleimide- and Disulfide-Based LinkersRachana Ohri, Sunil Bhakta, Aimee Fourie-O'Donohue, et al.
Science Translational Medicine|May 27, 2011
A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivoJasvinder K Atwal, Yongmei Chen, Cecilia Chiu, et al.
Bioorganic & Medicinal Chemistry Letters|August 2, 2016
Identification of potent, selective KDM5 inhibitorsVictor S Gehling, Steven F Bellon, Jean-Christophe Harmange, et al.
Bioorganic & Medicinal Chemistry Letters|July 14, 2016
Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studiesJun Liang, Birong Zhang, Sharada Labadie, et al.
Pageof 6

Showing results (31-40 of 54) with videos related to

Sort By:
Pageof 6
Mabs|January 31, 2020
Improved translation of stability for conjugated antibodies using an in vitro whole blood assayAimee Fourie-O'Donohue, Phillip Y Chu, Josefa Dela Cruz Chuh, et al.
Journal of Medicinal Chemistry|September 21, 2017
Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's DiseaseSnahel Patel, William J Meilandt, Rebecca I Erickson, et al.
Analytical Chemistry|December 12, 2023
Translatability of <i>In Vitro</i> Stress for Predicting Deamidation and Oxidation Biotransformation on BiotherapeuticsPhillip Y Chu, Hui Wang, Emily Ross, et al.
Journal of Medicinal Chemistry|October 3, 2015
Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N-(1H-Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12)Snahel Patel, Seth F Harris, Paul Gibbons, et al.
Bioorganic & Medicinal Chemistry Letters|August 9, 2016
Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitorsSharada S Labadie, Peter S Dragovich, Richard T Cummings, et al.
Bioorganic & Medicinal Chemistry Letters|September 10, 2013
Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenaseBenjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Bioconjugate Chemistry|February 10, 2018
High-Throughput Cysteine Scanning To Identify Stable Antibody Conjugation Sites for Maleimide- and Disulfide-Based LinkersRachana Ohri, Sunil Bhakta, Aimee Fourie-O'Donohue, et al.
Science Translational Medicine|May 27, 2011
A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivoJasvinder K Atwal, Yongmei Chen, Cecilia Chiu, et al.
Bioorganic & Medicinal Chemistry Letters|August 2, 2016
Identification of potent, selective KDM5 inhibitorsVictor S Gehling, Steven F Bellon, Jean-Christophe Harmange, et al.
Bioorganic & Medicinal Chemistry Letters|July 14, 2016
Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studiesJun Liang, Birong Zhang, Sharada Labadie, et al.
Pageof 6