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BMC Microbiology|December 14, 2011
Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNRI-Fen Liu, Sandra Aedo, Yuk-Ching Tse-Dinh
Journal of Molecular Biology|July 18, 2025
Search for Specific Inhibitors Targeting Type IA TopoisomerasesSomaia Haque Chadni, Shomita Ferdous, Yuk-Ching Tse-Dinh
Research Square|July 25, 2025
Networked Salt-Bridges Mediate Magnesium-Dependent Conformational Dynamics and Functional Regulation in Type IA TopoisomerasesYeonee Seol, Yuk-Ching Tse-Dinh, Keir C Neuman
Nature Structural & Molecular Biology|November 28, 2018
Direct observation of topoisomerase IA gate dynamicsMaria Mills, Yuk-Ching Tse-Dinh, Keir C Neuman
Nucleic Acids Research|December 22, 2007
Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase IBokun Cheng, Elena P Sorokin, Yuk-Ching Tse-Dinh
Nature Communications|April 30, 2026
Networked salt-bridges mediate magnesium-dependent conformational dynamics and functional regulation in type IA topoisomerasesYeonee Seol, Yuk-Ching Tse-Dinh, Keir C Neuman
BMC Biochemistry|June 13, 2009
Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocolThirunavukkarasu Annamalai, Neil Dani, Bokun Cheng, et al.
International Journal of Molecular Sciences|August 12, 2022
Microbial Type IA Topoisomerase C-Terminal Domain Sequence Motifs, Distribution and CombinationBrenda Diaz, Christopher Mederos, Kemin Tan, et al.
Methods in Molecular Biology (Clifton, N.J.)|November 28, 2017
A Fluorescence-Based Assay for Identification of Bacterial Topoisomerase I PoisonsThirunavukkarasu Annamalai, Bokun Cheng, Neelam Keswani, et al.
The Journal of Biological Chemistry|January 9, 2004
Flexibility at Gly-194 is required for DNA cleavage and relaxation activity of Escherichia coli DNA topoisomerase IBokun Cheng, Jingyang Feng, Sharvari Gadgil, et al.
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