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Anticancer Research|December 8, 2020
Application of Pharmacometrics of 5-Fluorouracil to Personalized Medicine: A Tool for Predicting Pharmacokinetic-Pharmacodynamic/Toxicodynamic ResponsesShinji Kobuchi, Yukako ItoThe Journal of Pharmacology and Experimental Therapeutics|July 15, 2024
Translational Pharmacokinetic-Toxicodynamic Model of Myelosuppression for Dose Optimization in Combination Chemotherapy of Capecitabine and Oxaliplatin from Rats to HumansShinji Kobuchi, Mayuka Arimoto, Yukako ItoEuropean Journal of Drug Metabolism and Pharmacokinetics|November 28, 2016
Population Pharmacokinetic-Pharmacodynamic Modeling of 5-Fluorouracil for Toxicities in RatsShinji Kobuchi, Yukako Ito, Toshiyuki SakaedaXenobiotica; the Fate of Foreign Compounds in Biological Systems|November 22, 2022
Predictive marker for exposure-driven haematological toxicity of tegafur-uracil and proposed modified-dosage regimen by pharmacometric approach in ratsShinji Kobuchi, Megumi Matsui, Yukako ItoXenobiotica; the Fate of Foreign Compounds in Biological Systems|April 3, 2019
Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation of oxaliplatin for hematological toxicity in ratsShinji Kobuchi, Yosuke Katsuyama, Yukako ItoCancers|December 24, 2021
Population Pharmacokinetic Model-Based Evaluation of Intact Oxaliplatin in Rats with Acute Kidney InjuryShinji Kobuchi, Miyu Kai, Yukako ItoJournal of Pharmaceutical Sciences|May 14, 2025
Chronopharmacokinetic model analysis of 5-fluorouracil following S-1 administration in rats: comparison with infusion and other prodrugs for chronochemotherapyShinji Kobuchi, Tomoki Satake, Yukako ItoPharmaceutics|February 8, 2020
Semi-Mechanism-Based Pharmacokinetic-Toxicodynamic Model of Oxaliplatin-Induced Acute and Chronic NeuropathyShinji Kobuchi, Risa Shimizu, And Yukako ItoDisaster Medicine and Public Health Preparedness|August 29, 2023
Children's Diet and Nutrition in the Aftermath of the Torrential Rain Disaster in Western Japan: An Evaluation of Support Activities by Dietitians to Alleviate Mothers' AnxietiesYukako Ito, Nobuyo Tsuboyama-Kasaoka, Hisae NakataniJournal of Pharmaceutical Sciences|April 21, 2020
Population Pharmacokinetic Model-Based Evaluation of Circadian Variations in Plasma 5-Fluorouracil Concentrations During Long-Term Infusion in Rats: A Comparison With Oral Anticancer ProdrugsShinji Kobuchi, Eisuke Matsumura, Yukako Ito, et al.Pageof 11