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ACS Medicinal Chemistry Letters|May 15, 2024
Discovery of Sovleplenib, a Selective Inhibitor of Syk in Clinical Development for Autoimmune Diseases and CancersHong Jia, Wei Deng, Baoyu Hao, et al.
ACS Medicinal Chemistry Letters|June 19, 2024
Structural Modifications of Covalent Cathepsin S Inhibitors: Impact on Affinity, Selectivity, and PermeabilityMergim Meta, Collin Zimmer, Natalie Fuchs, et al.
ACS Medicinal Chemistry Letters|May 15, 2024
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 InhibitorsPhilippe N Bolduc, Magnus Pfaffenbach, Ryan Evans, et al.
ACS Medicinal Chemistry Letters|May 15, 2024
Structure-Activity Relationship Study of Biselyngbyolide B Reveals Mitochondrial Fission-Induced Cytotoxicity in CancerPratiti Mandal, Debobrata Paul, Himangshu Sharma, et al.
ACS Medicinal Chemistry Letters|May 15, 2024
Transforming Therapeutic Approaches with PROTAC Technology: New Targets and PotentialsRobert B Kargbo
ACS Medicinal Chemistry Letters|May 15, 2024
Identification of Selective Imidazopyridine CSF1R InhibitorsJohn L Kane, Gary Asmussen, Joseph Batchelor, et al.
ACS Medicinal Chemistry Letters|May 15, 2024
Efficient Radiolabeling of Proteins and Antibodies via Maleamate-Cysteine BioconjugationSajid Mushtaq, Kyo Chul Lee, Ji Ae Park, et al.
ACS Medicinal Chemistry Letters|December 17, 2025
Development and Evaluation of 1‑Hydroxypyridin-2(1H)‑one Derivatives as Antibacterial Agents against Pathogenic Pseudomonas aeruginosaSandesha Nayak, Berehe Solomon Girmay, Ha Jeong Byun, et al.
ACS Medicinal Chemistry Letters|December 17, 2025
Discovery of a Novel Template, N3‑1'-Homologated 4'-Truncated Thiosugar-Substituted Xanthine as an A3AR Antagonist via Conversion of an A1AR AntagonistMisuk Joung, Minjae Kim, Hongseok Choi, et al.
ACS Medicinal Chemistry Letters|December 17, 2025
Dual Innovations in EGFR Degradation and Antigen-Specific Modulation for Multiple SclerosisAnna C Renner, Robert B Kargbo
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