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Bioorganic Chemistry|November 21, 2025
Rational design of next-generation PDK1 modulators: Addressing selectivity and resistance through molecular insights - A medicinal chemistry perspectiveYuxing Fu, Yuxuan Zhu, Xin Zhou, et al.
Bioorganic Chemistry|November 20, 2025
Synthesis and antioxidant activity of paeoniflorin derivativesQian Xiao, YuXiang Song, Meng Yang, et al.
Bioorganic Chemistry|November 15, 2025
ZnO nanoparticles enhance the cytotoxic effects of a chalcone-sulfonamide hybrid by impairing the autophagic flux and upregulating HIF-1α expressionJessica Maria Teles Souza, Stéphanie Aguiar de Negreiros Matos Silva, Rodrigo Elísio de Sá, et al.
Bioorganic Chemistry|November 15, 2025
Responsive fluorescent probes for the imaging of cancerShengyao Wang, Xiaojuan Yang, Zhe Zhang, et al.
Bioorganic Chemistry|November 17, 2025
PD-L1-targeted novel molecule design: recent advances in immunomodulatory technologies and emerging insights in Cancer therapyFeng Zhang, Ruyue Ni, Liang Qian, et al.
Bioorganic Chemistry|November 8, 2025
Phyto-engineered palladium-gold bimetallic core-shell nanoparticles utilising aq.cranberry fruit extract for photocatalytic reduction and biomedical applicationsJ Edal Queen, Fahd A Nasr, T Augustine Arul Prasad, et al.
Bioorganic Chemistry|January 23, 2026
Phenylpiperazine/dithioates as novel H2S donors: design, synthesis, H2S release, formulation as PEG-niosomes and antifungal activity against Candida albicansGhada M Sadiq, Mohamed A Mawhoup, Mai M M Tawfik, et al.
Bioorganic Chemistry|January 22, 2026
Copper(II)-catalysed one-pot synthesis of thiazole/benzothiazole-based isoquinolin-1(2H)-ones as potential cytotoxic and VEGFR-2 inhibitorsShivam Gupta, A Ezhilmathe, Mary Sravani Galla, et al.
Bioorganic Chemistry|January 22, 2026
Novel 5,7-Diazaindole-based ERK5 inhibitor induces endoplasmic reticulum stress and mitochondrial apoptosis in non-small cell lung CancerBinbin Tian, Yunjie Li, Pengyu Xue, et al.
Bioorganic Chemistry|January 8, 2026
Optimized co-fermentation strategy for efficient production of Dihydro-β-ionone from β-Ionol using engineered Escherichia coli and Saccharomyces cerevisiaeKaixuan Ke, Jiafeng Li, Huilin Xie, et al.
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