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Bioorganic Chemistry|June 16, 2026
Evaluation of the biological potential of N-(1-ferrocenyl-2-(methylthio)ethyl)anilines: antimicrobial, antioxidant, DNA-binding, and molecular docking studiesJovana Bugarinović, Jelena Stepanović, Marko Pešić, et al.Bioorganic Chemistry|June 16, 2026
Discovery of fluoxakalner, a novel and preferential Kv7.2/7.3 channel opener for antinociception in miceWei Xiang, Yaxuan Qu, Xiangyang Kong, et al.Bioorganic Chemistry|June 17, 2026
Design and synthesis of 1-Phenyl-2-thioaryl-4-benzyl-5-methylimidazoles as dual STAT3/NF-κB inhibitors for triple-negative breast Cancer therapyAmira A Abdellatef, Ahmed K Al-Kubeisi, Salwa M Fahmy, et al.Bioorganic Chemistry|July 19, 2023
Development of pyrolo[2,3-c]pyrazole, pyrolo[2,3-d]pyrimidine and their bioisosteres as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological evaluation and molecular dynamics investigationsEman M Azmy, Mohamed Hagras, Menna A Ewida, et al.Bioorganic Chemistry|July 16, 2023
1H NMR-guided isolation of hasubanan alkaloids from the alkaloidal extract of Stephania longaJiao Xiao, Yingjie Wang, Yanqiu Yang, et al.Bioorganic Chemistry|July 1, 2023
Salinization Dramatically Enhance the Anti-Prostate Cancer Efficacies of AR/AR-V7 and Mnk1/2 Molecular Glue Degraders, Galeterone and VNPP433-3β Which Outperform Docetaxel and Enzalutamide in CRPC CWR22Rv1 Xenograft Mouse ModelRetheesh S Thankan, Elizabeth Thomas, Puranik Purushottamachar, et al.Bioorganic Chemistry|June 30, 2023
Phakellisins A-E, cyclopeptides from a marine sponge Phakellia sp. guided by LC-MSCan Kong, Ying Wu, Hui-Min Zhao, et al.Bioorganic Chemistry|June 28, 2023
Discovery of dual PARP and CDK6 inhibitors for triple-negative breast cancer with wild-type BRCACheng Wang, Heng Luo, Xinye Chen, et al.Bioorganic Chemistry|June 30, 2023
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase IMi Zhang, Li-Zu Zhu, Cheng-Jie Yang, et al.Bioorganic Chemistry|June 23, 2023
Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNTPeizhuo Li, Yucheng Tian, Qinghong Shang, et al.Pageof 868