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Bioorganic Chemistry|August 27, 2026
Bioorganic strategies for quorum sensing inhibition: disrupting biofilms and virulence in drug-resistant pathogensMo Ahamad Khan, Lechen Zhu, Xinyu Zhu, et al.
Bioorganic Chemistry|August 31, 2026
A rationally designed PglB mutant with increased in vivo O86-reactive AcrA signal for glycoprotein productionJiang-Yu Yang, Xue-Qing Guo, Qi-Xiu Yue, et al.
Bioorganic Chemistry|August 31, 2026
Targeting autophagy-dependent cell death in cancer therapy: An update on small-molecule compoundsYuzhe Yang, Mengqiao Chen, Qiang Xie, et al.
Bioorganic Chemistry|August 24, 2026
Design and synthesis of long-acting prodrugs of SEP-363856 with sustained antipsychotic-like activityWenjing Gao, Yunlin Xue, Jiyang Zhang, et al.
Bioorganic Chemistry|September 16, 2026
Deoxycalyxin A exerts hypoglycemic effects through activating TGR5-induced GLP-1 secretion via TGR5/PKA/MEK/ERK pathwaySheng-Li Wu, Xiao-Feng He, Pianchou Gongpan, et al.
Bioorganic Chemistry|September 20, 2026
Prebiotic peptide formation triggered by urea-rich warm little ponds on early earthYuqi Liu, Shaohua Huang
Bioorganic Chemistry|September 21, 2026
Thieno[2,3-d]pyrimidine scaffold optimization for synergistic c-Met/STAT3 blockade: Synthesis, structure-activity relationships, in vitro potency, and apoptotic pathways in colorectal cancerShaimaa I El-Desouky, Hesham Haffez, Mohamed S Nafie, et al.
Bioorganic Chemistry|September 9, 2026
Mesona chinensis Benth polyphenols ameliorate type 2 diabetes mellitus in mice through coordinated regulation of gut microbiota, metabolic profiles, and host metabolic-inflammatory responsesChushan Chen, Qinghui He, Haoheng Cao, et al.
Bioorganic Chemistry|September 9, 2026
New oxa/thiadiazole-chalcone hybrids linked via a clickable 1,2,3-triazole bridge with dual EGFR/VEGFR-2 kinase inhibitory activity and antiproliferative effectsMerit El-Qommos, Rana M I Morsy, Hamdy M Abdel-Rahman, et al.
Bioorganic Chemistry|September 22, 2026
Homo-aro-cholestane glycosides from Ypsilandra thibetica modulate the expansion of human cord blood hematopoietic stem and progenitor cellsXu-Hong Li, Jia-Hui Ma, Tao-Bin He, et al.
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