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Chemmedchem|July 22, 2014
6-Hydroxybenzothiophene ketones: potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) owing to favorable molecule geometry and conformational preorganizationParisa Miralinaghi, Christian Schmitt, Rolf W Hartmann, et al.
Chemmedchem|July 22, 2014
Importance of the 6'-hydroxy group and its configuration for apramycin activityAppi Reddy Mandhapati, Dimitri Shcherbakov, Stefan Duscha, et al.
Chemmedchem|July 23, 2014
Amphiphilic bicyclic peptides as cellular delivery agentsDonghoon Oh, Shaban Anwar Darwish, Amir Nasrolahi Shirazi, et al.
Chemmedchem|August 23, 2014
Structure-activity relationship, biological, and pharmacological characterization of the proline sulfonamide ACT-462206: a potent, brain-penetrant dual orexin 1/orexin 2 receptor antagonistChristoph Boss, Catherine Roch-Brisbare, Michel A Steiner, et al.
Chemmedchem|August 10, 2013
Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptorJin Xu, Anqi Chen, Joma Joy, et al.
Chemmedchem|August 10, 2013
CONFECT: conformations from an expert collection of torsion patternsChristin Schärfer, Tanja Schulz-Gasch, Jérôme Hert, et al.
Chemmedchem|August 10, 2013
In silico optimization of a fragment-based hit yields biologically active, high-efficiency inhibitors for glutamate racemaseKatie L Whalen, Anthony C Chau, M Ashley Spies
Chemmedchem|August 3, 2013
A parallel semisynthetic approach for structure-activity relationship studies of peptide YYLouise Albertsen, Søren Østergaard, Johan F Paulsson, et al.
Chemmedchem|September 17, 2013
Metal-based compounds as prospective antileishmanial agents: inhibition of trypanothione reductase by selected gold complexesGianni Colotti, Andrea Ilari, Annarita Fiorillo, et al.
Chemmedchem|August 15, 2013
A conformational mimetic approach for the synthesis of carbocyclic nucleosides as anti-HCV leadsMohan Kasula, Tuniki Balaraju, Massaki Toyama, et al.
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