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Clinical and Translational Science|October 2, 2025
Trends in and Determinants of Approval Lag for Anticancer Drugs in Japan and the US: Role of Multi-Regional Trials and Concurrent ApprovalsHitoshi Kanno, Kotone Matsuyama
Clinical and Translational Science|September 30, 2025
Impact of Dose-Escalation Design on the Safety and Development of Anticancer Drugs in Clinical TrialsAtsushi Nonami, Kensuke Matsuda, Kouta Funakoshi, et al.
Clinical and Translational Science|August 31, 2021
Upadacitinib pharmacokinetics and exposure-response analyses of efficacy and safety in psoriatic arthritis patients - Analyses of phase III clinical trialsElena Muensterman, Benjamin Engelhardt, Sathej Gopalakrishnan, et al.
Clinical and Translational Science|September 20, 2025
Role of Trimethylamine N-Oxide in Assessing Plaque Instability of the Culprit Lesion in Chinese Patients With ST-Elevation Myocardial Infarction: Insights From a 7-Year Long-Term Follow-Up StudyLili Xiu, Peng Zhao, Xia Gu, et al.
Clinical and Translational Science|August 4, 2025
Retrospective Analysis of Master Protocols in Tumor-Agnostic Drug Development: Evaluation of Application to Single-Agent Therapies With ORR as the Endpoint for Approval of Oncology DrugsKeiko Yamamoto, Kentaro Takeda, Hideki Maeda
Clinical and Translational Science|August 5, 2025
APOE Genotype and Statin Response: Evidence From the UK Biobank and All of Us ProgramInnocent G Asiimwe, Andrea L Jorgensen, Munir Pirmohamed, et al.
Clinical and Translational Science|August 5, 2025
Model-Informed Paradigm in Drug Development-An End-To-End Case Study From Upadacitinib DevelopmentSumit Bhatnagar, Sven Stodtmann, Yuli Qian, et al.
Clinical and Translational Science|August 26, 2021
REGN1908-1909 monoclonal antibodies block Fel d 1 in cat allergic subjects: Translational pharmacokinetics and pharmacodynamicsMohamed A Kamal, Robert Dingman, Claire Q Wang, et al.
Clinical and Translational Science|August 11, 2021
Microphysiological systems in absorption, distribution, metabolism, and elimination sciencesKirk P Van Ness, Francine Cesar, Catherine K Yeung, et al.
Clinical and Translational Science|May 1, 2021
Pharmacokinetics and tolerability of apremilast in healthy Korean adult menKi Young Huh, Yewon Choi, Jim Nissel, et al.
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