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European Journal of Medicinal Chemistry|June 6, 2022
Therapeutic potentials and structure-activity relationship of 1,3-benzodioxole N-carbamothioyl carboxamide derivatives as selective and potent antagonists of P2X4 and P2X7 receptorsAbid Mahmood, Alexander Villinger, Jamshed IqbalEuropean Journal of Medicinal Chemistry|June 6, 2022
Bacterial type I signal peptidase inhibitors - Optimized hits from natureNatalia Szałaj, Andrea Benediktsdottir, Dominika Rusin, et al.European Journal of Medicinal Chemistry|June 6, 2022
Identification of non-ATP-competitive α-carboline inhibitors of the anaplastic lymphoma kinaseLuca Mologni, Alexandre Orsato, Alfonso Zambon, et al.European Journal of Medicinal Chemistry|May 31, 2022
Synthetic derivatives of the antifungal drug ciclopirox are active against herpes simplex virus 2Maryam Zangi, Katherine A Donald, Andreu Gazquez Casals, et al.European Journal of Medicinal Chemistry|May 31, 2022
Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studiesYiming Xu, Yulong Xu, Hallie Blevins, et al.European Journal of Medicinal Chemistry|May 31, 2022
Ring replacement recommender: Ring modifications for improving biological activityPeter Ertl, Eva Altmann, Sophie Racine, et al.European Journal of Medicinal Chemistry|May 31, 2022
Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degraderCheng-Liang Zhu, Xiaomin Luo, Tian Tian, et al.European Journal of Medicinal Chemistry|June 1, 2022
Design and synthesis of highly TRAIL expression HDAC inhibitors based on ONC201 to promote apoptosis of colorectal cancerHao Cui, Zan Hu, Kang Yang, et al.European Journal of Medicinal Chemistry|June 10, 2022
Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main proteaseXiaodong Dou, Qi Sun, Guofeng Xu, et al.European Journal of Medicinal Chemistry|June 12, 2022
Pan- and isoform-specific inhibition of Hsp90: Design strategy and recent advancesJing Yu, Chao Zhang, Chun SongPageof 1,615