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European Journal of Medicinal Chemistry|April 12, 2017
Design, synthesis, and evaluation of curcumin derivatives as Nrf2 activators and cytoprotectors against oxidative deathZhi-Shan Tu, Qi Wang, Dan-Dan Sun, et al.
European Journal of Medicinal Chemistry|April 11, 2017
Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC)Zhendong Song, Shanshan Huang, Haiqing Yu, et al.
European Journal of Medicinal Chemistry|November 13, 2021
Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activationJinxin Che, Canliang Ma, Jialiang Lu, et al.
European Journal of Medicinal Chemistry|November 13, 2021
Construction and activity evaluation of novel dual-target (SE/CYP51) anti-fungal agents containing amide naphthyl structureWenxia Liu, Zhuang Sun, Yunfei An, et al.
European Journal of Medicinal Chemistry|November 6, 2021
Discovery and optimization of cyclohexane-1,4-diamines as allosteric MALT1 inhibitorsStefan Schiesser, Peter Hajek, Huw E Pople, et al.
European Journal of Medicinal Chemistry|November 6, 2021
Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles-resistant Candida albicansChaochen Li, Jie Tu, Guiyan Han, et al.
European Journal of Medicinal Chemistry|November 8, 2021
Broadening antifungal spectrum and improving metabolic stablity based on a scaffold strategy: Design, synthesis, and evaluation of novel 4-phenyl-4,5-dihydrooxazole derivatives as potent fungistatic and fungicidal reagentsWenbo Yin, Hengxian Cui, Hong Jiang, et al.
European Journal of Medicinal Chemistry|November 30, 2021
Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine-Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitorsHeba T Abdel-Mohsen, Ahmed M El Kerdawy, Mohamed A Omar, et al.
European Journal of Medicinal Chemistry|November 30, 2021
Straightforward access to novel mitochondriotropics derived from 2-arylethanol as potent and selective antiproliferative agentsFrancisco J Hicke, Adrián Puerta, Jelena Dinić, et al.
European Journal of Medicinal Chemistry|December 5, 2021
Noncovalent CDK12/13 dual inhibitors-based PROTACs degrade CDK12-Cyclin K complex and induce synthetic lethality with PARP inhibitorTian Niu, Kailin Li, Li Jiang, et al.
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