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Investigational New Drugs|December 20, 2013
Phase I study of MLN8237--investigational Aurora A kinase inhibitor--in relapsed/refractory multiple myeloma, non-Hodgkin lymphoma and chronic lymphocytic leukemiaKevin R Kelly, Thomas C Shea, André Goy, et al.
Investigational New Drugs|March 23, 2016
Phase 1 study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in Japanese patients with advanced solid tumorsToshio Shimizu, Takashi Seto, Fumihiko Hirai, et al.
Investigational New Drugs|March 29, 2016
Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparisonAnne-Charlotte Dubbelman, Cynthia M Nijenhuis, Robert S Jansen, et al.
Investigational New Drugs|April 9, 2016
A phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with metastatic melanomaShailender Bhatia, Anna C Pavlick, Peter Boasberg, et al.
Investigational New Drugs|August 19, 2017
Effect of alisertib, an investigational aurora a kinase inhibitor on the QTc interval in patients with advanced malignanciesXiaofei Zhou, John Nemunaitis, Shubham Pant, et al.
Investigational New Drugs|July 29, 2017
A Phase I study to determine safety, pharmacokinetics, and pharmacodynamics of ANF-RHO™, a novel PEGylated granulocyte colony-stimulating factor, in healthy volunteersHemant Misra, John Berryman, Ronald Jubin, et al.
Investigational New Drugs|October 26, 2017
Posterior reversible encephalopathy syndrome (PRES) induced by pazopanib, a multi-targeting tyrosine kinase inhibitor, in a patient with soft-tissue sarcoma: case report and review of the literatureShoichi Deguchi, Koichi Mitsuya, Yoko Nakasu, et al.
Investigational New Drugs|October 14, 2017
Clinical toxicity of antibody drug conjugates: a meta-analysis of payloadsJoanna C Masters, Dana J Nickens, Dawei Xuan, et al.
Investigational New Drugs|November 12, 2017
A phase 2 study of ontuxizumab, a monoclonal antibody targeting endosialin, in metastatic melanomaSandra P D'Angelo, Omid A Hamid, Ahmad Tarhini, et al.
Investigational New Drugs|November 9, 2017
Cyclodextrin polymers as nanocarriers for sorafenibValentina Giglio, Maurizio Viale, Vittorio Bertone, et al.
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