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Science Signaling|July 15, 2025
Autophosphorylation of oncoprotein TEL-ABL in myeloid and lymphoid cells confers resistance to the allosteric ABL inhibitor asciminibSerena Muratcioglu, Christopher A Eide, Chien-Lun Hung, et al.Science Signaling|May 6, 2025
Insights into the intramembrane protease SPPL2b and its substrates: Functions and disease implicationsJack Badman, Antonietta Parracino, Rajnish Kumar, et al.Science Signaling|October 28, 2025
Loss of the conserved switch III region in a G protein leads to severe pediatric encephalopathyMikhail Savitsky, Yonika A Larasati, Gonzalo P Solis, et al.Science Signaling|October 7, 2025
An ectopic Hedgehog signaling axis drives directional tumor outgrowth in a mouse model of hereditary multiple osteochondromasSarah E Catheline, Christina Mundy, Cheri Saunders, et al.Science Signaling|September 9, 2025
Identification of proteins in semen-derived extracellular vesicles that bind to Tat and NF-κB and that may impair HIV replicationBryson C Okeoma, Hussein Kaddour, Wasifa Naushad, et al.Science Signaling|September 9, 2025
Fusobacterium nucleatum enhances amphetamine-induced behavioral responses through a butyrate-driven epigenetic mechanismSamuel J Mabry, Xixi Cao, Yanqi Zhu, et al.Science Signaling|August 12, 2025
The kinase ERK plays a conserved dominant role in the heterogeneity of epithelial-mesenchymal transition in pancreatic cancer cellsMichelle C Barbeau, Brooke A Brown, Sara J Adair, et al.Pageof 320