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Science Signaling|January 27, 2026
T cell polarization and NFAT activation are stiffness dependent and differentially regulated by the channels PIEZO1 and ORAI1Renping Zhao, Jingnan Zhang, Sijia Zhang, et al.Science Signaling|January 27, 2026
EGFR activation sensitizes trigeminal NMDA receptors to promote pain and morphine analgesic tolerance in oral cancerNaijiang Liu, Xiaojie Shi, Shao-Rui Chen, et al.Science Signaling|April 8, 2025
The antipsychotic drug thiothixene stimulates macrophages to clear pathogenic cells by inducing arginase 1 and continual efferocytosisYoko Kojima, Zhongde Ye, Fudi Wang, et al.Science Signaling|April 15, 2025
Dynamic modulation of the motor neuron translatome during developmental synapse eliminationDinja van der Hoorn, Fabio Lauria, Helena Chaytow, et al.Science Signaling|February 24, 2026
Temporal proteomic and phosphoproteomic dynamics during neuronal differentiation in the reference iPSC line KOLF2.1JYing Hao, Ziyi Li, Erika Lara, et al.Science Signaling|March 17, 2026
The unphosphorylated, closed form of ezrin binds to RNA to maintain a metastatic phenotype in osteosarcoma cellsEmre Deniz, Prakriti Tiwari, Purushottam B Tiwari, et al.Science Signaling|February 6, 2024
A mammalian-specific Alex3/Gαq protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survivalIsmael Izquierdo-Villalba, Serena Mirra, Yasmina Manso, et al.Pageof 320