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The AAPS Journal|November 18, 2025
Leveraging in vitro Tumor Cell Killing and Cytokine Release to Predict Cytokine Release Syndrome Associated with CD3 T-cell Bispecifics in Oncology: a Retrospective AnalysisApolline Lefèvre, Zinnia P Parra-Guillen, Iñaki F Trocóniz, et al.The AAPS Journal|November 11, 2025
Regulatory Divergence in Narrow Therapeutic Index Drugs: A Comparative Review of the US, EU, Japan, Canada, and South KoreaSieun Lee, Jiwon Baek, Wonku Kang, et al.The AAPS Journal|January 8, 2026
Virtual Twin-PBPK Modelling: A Step Toward Precision Dosing in Patients with ObesityHaribhau Kangne, Nihan Izat, Gong Chen, et al.The AAPS Journal|January 6, 2026
Exploration of IVIVC Deconvolution Methods in a PBPK Platform: Case Example with TofacitinibBart HensThe AAPS Journal|October 24, 2025
Mechanistic Modeling of Intramuscular Administration of a Long-acting Injectable Accounting for Tissue Response At the Depot SiteDaniela A Silva, Maxime Le Merdy, James Mullin, et al.The AAPS Journal|October 31, 2025
Integrated Physiologically-based Pharmacokinetic Model with a Quantitative Systems Pharmacology and Toxicology Model for Statins in Disease Population. Part 2: MIDD and MIPD ApplicationsLuna Prieto Garcia, Pär Nordell, Christine Ahlström, et al.The AAPS Journal|October 14, 2025
Patient-Centric Drug Product Quality Specifications: a Convergence of Clinical and Nonclinical ConsiderationsStan Altan, Hans Coppenolle, Trine Kvist, et al.The AAPS Journal|October 14, 2025
Effective Visualizations Using "vachette" to Assess and Communicate Pharmacometric Model ResultsJos Lommerse, Anna Largajolli, James Craig, et al.The AAPS Journal|October 13, 2025
A Proxy-guided Workflow for Virtual Population DevelopmentLu Huang, Yinbo Chen, Satyendra Suryawanshi, et al.The AAPS Journal|October 9, 2025
Physiologically Based Pharmacokinetic Modeling and Simulation in Regulatory Review: US FDA CBER Experience and PerspectivesMillion A Tegenge, Osman N Yogurtcu, Artur A Belov, et al.Pageof 235