Antoine Desilets

9PUBLICATIONS
28CO-AUTHORS
Medical infection agents (incl. prions)Toxicology (incl. clinical toxicology)Medical molecular engineering of nucleic acids and proteinsProteins and peptidesNanotoxicology, health and safety
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Publications (9)

|Sep 10, 2026
Discovery of Highly Selective Noncovalent Macrocyclic Peptide Inhibitors Suppressing Both TMPRSS2 Protease Activity and Viral Receptor Function.

|Dec 05, 2025
Structure-Guided Optimization of Selective Covalent Reversible Peptidomimetic Inhibitors Targeting TMPRSS6.

Walid Guerrab, Matthieu Lepage, Antoine Désilets

|Mar 31, 2025
From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 Variants.

Gabriel Lemieux, Jimena Pérez-Vargas, Antoine Désilets

|Sep 11, 2024
Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency.

Alexandre Joushomme, Antoine Désilets, William Champagne

|Jul 19, 2024
Rational In Silico Design of Selective TMPRSS6 Peptidomimetic Inhibitors via Exploitation of the S2 Subpocket.

Michael Desgagné, Antoine Désilets, Sára Ferková

|Oct 21, 2023
Optimization of Ketobenzothiazole-Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication.

Éloïc Colombo, Antoine Désilets, Malihe Hassanzadeh

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Frequent Collaborators

6 joint publications

Pierre-Luc Boudreault

5 joint publications

Gabriel Lemieux

3 joint publications

Richard Leduc

2 joint publications

Michael Desgagné