François Jean

8PUBLICATIONS
49CO-AUTHORS
Pharmaceutical delivery technologiesMedical molecular engineering of nucleic acids and proteinsCheminformatics and quantitative structure-activity relationshipsBiologically active moleculesProteins and peptides
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Publications (8)

|Jun 12, 2026
A reversible broad-spectrum antiviral targets the human V-ATPase VO domain.

|Mar 31, 2025
From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 Variants.

Gabriel Lemieux, Jimena Pérez-Vargas, Antoine Désilets

|Aug 09, 2023
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.

Jimena Pérez-Vargas, Liam J Worrall, Andrea D Olmstead

|Jun 26, 2023
Synthetic Analogs of the Sponge Sesterterpenoid Alotaketal C are Potent Inhibitors of SARS-CoV-2 Omicron BA.1 and BA.5 Infections of Human Lung Cells.

Polina Blagojevic, Jimena Perez-Vargas, Kunzhong Jian

|Dec 12, 2022
Inhibition of glycogen synthase kinase-3-beta (GSK3β) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication.

Tirosh Shapira, Selvarani Vimalanathan, Celine Rens

|Mar 28, 2022
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.

Tirosh Shapira, I Abrrey Monreal, Sébastien P Dion

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Frequent Collaborators

4 joint publications

Andrea D Olmstead

4 joint publications

Pierre-Luc Boudreault

3 joint publications

Richard Leduc

2 joint publications

Ivan Robert Nabi