Christoph M Dehnhardt

5PUBLICATIONS
9CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsNeurology and neuromuscular diseases
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Publications (5)

|Sep 15, 2026
Discovery of Novel Bicyclic Pyrazole Amides as Potent Neuronal KV7 Potassium Channel Openers with Strong Preclinical Antiseizure Activity.

|Mar 08, 2021
Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310.

Brian S Safina, Steven J McKerrall, Shaoyi Sun

|Sep 19, 2019
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy.

Thilo Focken, Kristen Burford, Michael E Grimwood

|Apr 04, 2019
Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Nav1.7 Inhibitors for the Treatment of Chronic Pain.

Steven J McKerrall, Teresa Nguyen, Kwong Wah Lai

|Dec 01, 2018
Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (NaV) 1.7 with Potent Analgesic Activity.

Shaoyi Sun, Qi Jia, Alla Y Zenova

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Frequent Collaborators

3 joint publications

Thilo Focken

2 joint publications

Steven J McKerrall

1 joint publications

Benjamin D Sellers

1 joint publications

Brian S Safina