Murugaiah A M Subbaiah

22PUBLICATIONS
22CO-AUTHORS
Pharmaceutical delivery technologiesMolecular targetsFunctional materialsBiologically active moleculesApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)
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Publications (22)

|Jun 08, 2026
Drug Delivery Strategy Exploiting Amino Acid Prodrugs: Improving Oral Bioavailability and Overcoming Nonlinear Pharmacokinetic Challenges Following Dose Escalation of a CK2 Inhibitor with Poor Solubility.

|May 20, 2026
Discovery of BMS-159, an Orally Active Imidazotriazine Pan-CK2 Inhibitor for the Treatment of Cancer.

|Mar 30, 2026
From Flat to 3D: Replacing Phenyl Rings with Saturated Bridged Bicyclic Mimetics to Mitigate Bioactivation and Optimize ADME Properties and Oral Bioavailability in Reverse Amide Orientation.

Murugaiah A M Subbaiah, Shruti Surendran, Gaurav Saini

|Jan 07, 2026
Enhancing the Oral Bioavailability of a Poorly Soluble Pan-CK2 Kinase Inhibitor: Leveraging a Phosphate Prodrug Strategy to Overcome Dissolution-Limited Absorption and Improve Systemic Exposure during Dose Escalation.

Murugaiah A M Subbaiah, Naveen Manjunath, Thangeswaran Ramar

|Oct 01, 2025
Beyond Bioisosteres: Impact of Replacing a Benzene Ring with sp3-Rich Three-Dimensional Saturated Bridged Bicyclic Match Pairs on Biotransformation, Metabolic Stability, and Other ADME Profiles.

Shruti Surendran, Sivashankaran Raju, Naveen Kalyani

|Jan 15, 2025
Structure-Based Design of Novel TLR7/8 Agonist Payloads Enabling an Immunomodulatory Conjugate Approach.

Yam B Poudel, Julian C Lo, Derek J Norris

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Frequent Collaborators

7 joint publications

Andivelu Ilangovan

6 joint publications

Nicholas A Meanwell

4 joint publications

Ashvinikumar V Gavai

3 joint publications

Anuradha Gupta