Lyn-Marie Birkholtz

29PUBLICATIONS
114CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMedical parasitologyBiologically active moleculesMolecular targetsBiomolecular modelling and design
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Publications (29)

|Jun 13, 2026
The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of PfArk1 and Hemozoin Formation.

|Mar 31, 2026
Protein Arginine Methyltransferase Inhibitors Target Multiple Stages of Plasmodium falciparum Parasites In Vitro.

Daniel Opperman, Tayla Rabie, Marché Maré

|Jan 14, 2026
A Novel Class of Orally Bioavailable Phenylglycine-Benzoxaborole Conjugates with Antimalarial Activity and Potentially Novel Mechanism of Action.

Mokhitli Morake, Dale Taylor, Dina Coertzen

|Oct 24, 2025
Targeting Aurora Kinases as Essential Cell-Cycle Regulators to Deliver Multi-Stage Antimalarials Against Plasmodium Falciparum.

Henrico Langeveld, Keletso Maepa, Marché Maree

|Aug 14, 2025
Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model.

Godwin A Dziwornu, Mmakwena M Mmonwa, Dina Coertzen

|May 16, 2025
Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual Plasmodium Phosphatidylinositol 4-Kinase Beta and cGMP-Dependent Protein Kinase Inhibitor, for Malaria.

Samuel Gachuhi, Stephanie Kamunya, Stephen Fienberg

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Frequent Collaborators

9 joint publications

Kelly Chibale

4 joint publications

Lauren B Coulson

4 joint publications

Janette Reader

3 joint publications

Dina Coertzen