Lauren B Coulson

9PUBLICATIONS
42CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designPharmacogenomicsBiologically active molecules
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Publications (9)

|Jun 13, 2026
The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of PfArk1 and Hemozoin Formation.

|Jan 14, 2026
Repositioning a Human Kinase Platelet-Derived Growth Factor Receptor Alpha Type II Inhibitor for Malaria and Inhibition of Hemozoin Formation.

Mmakwena M Mmonwa, Oluwatosin Audu, Keletso Maepa

|Oct 07, 2025
Optimization of 2,8-Diaryl-1,5-naphthyridines as Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo Efficacy.

Godwin A Dziwornu, Donald Seanego, Stephen Fienberg

|Aug 14, 2025
Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model.

Godwin A Dziwornu, Mmakwena M Mmonwa, Dina Coertzen

|May 16, 2025
Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual Plasmodium Phosphatidylinositol 4-Kinase Beta and cGMP-Dependent Protein Kinase Inhibitor, for Malaria.

Samuel Gachuhi, Stephanie Kamunya, Stephen Fienberg

|Apr 01, 2025
Design of Novel Mercapto-3-phenylpropanoyl Dipeptides as Dual Angiotensin-Converting Enzyme C-Domain-Selective/Neprilysin Inhibitors.

Gyles E Cozier, Lauren B Coulson, Charles J Eyermann

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Frequent Collaborators

7 joint publications

Kelly Chibale

4 joint publications

Lyn-Marie Birkholtz

3 joint publications

Godwin A Dziwornu

3 joint publications

Kathryn J Wicht