Yossi Zafrani

16PUBLICATIONS
22CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiologically active moleculesBiomolecular modelling and designF-block chemistryNatural products and bioactive compounds
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Publications (16)

|Feb 12, 2026
From NH+ Chemical Shifts to Chemical Insights: A 1H NMR Spectroscopic Window into Amine pKa, Anion pKBHX, and Charge-Assisted Intramolecular H-Bond Assessment from a Medicinal Chemistry Perspective.

Shlomi Elias, Dafna Amir, Boris Smolkin

|Jul 16, 2024
Addressing the Opioids Lipophilicity Challenge via a Straightforward and Simultaneous 1H NMR-Based logP/D Determination, Both Separately and in Mixtures.

Dina Yeffet, Ishay Columbus, Galit Parvari

|Jul 11, 2024
CF2H: a fascinating group for application in drug development enabling modulation of many molecular properties.

Sigal Saphier, Yossi Zafrani

|Sep 15, 2023
Species-specific lipophilicities of fluorinated diketones in complex equilibria systems and their potential as multifaceted reversible covalent warheads.

Ishay Columbus, Lee Ghindes-Azaria, Ido Michael Herzog

|Nov 14, 2022
Placing CF2 in the Center: Major Physicochemical Changes Upon a Minor Structural Alteration in Gem-Difunctional Compounds.

Sigal Saphier, Shahaf Katalan, Guy Yacov

|Jul 05, 2022
Software-Assisted Automated Detection and Identification of "Unknown" Analogues: Implementation on V-Type Nerve Agents.

Eyal Drug, Eytan Gershonov, Nissan Ashkenazi

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Frequent Collaborators

8 joint publications

Ishay Columbus

8 joint publications

Sigal Saphier

5 joint publications

Gil Fridkin

5 joint publications

Yoav Eichen