David Yin-Wei Lin

5PUBLICATIONS
12CO-AUTHORS
Biologically active moleculesStructural biology (incl. macromolecular modelling)Autonomic nervous systemApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Gene and molecular therapy
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Publications (5)

|May 18, 2026
More than an attachment module: covalent inhibitor warheads influence BTK dynamics and function.

|Jan 08, 2024
Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states.

David Yin-Wei Lin, Lauren E Kueffer, Puneet Juneja

|Oct 03, 2023
Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states.

David Yin-Wei Lin, Lauren E Kueffer, Puneet Juneja

|Aug 31, 2023
Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib.

David Y Lin, Amy H Andreotti

|Sep 20, 2022
The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction.

Manish Aryal, David Lin, Kiera Regan

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Frequent Collaborators

3 joint publications

Amy H Andreotti

2 joint publications

Thomas E Wales

2 joint publications

John R Engen

1 joint publications

Manish Aryal