Xiangyi Jiang

6PUBLICATIONS
12CO-AUTHORS
Medical molecular engineering of nucleic acids and proteinsBiologically active moleculesCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and design
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Publications (6)

|Jul 13, 2026
Targeted Degradation of Capsid by Host-Hijacking PROTAC Overcomes Drug Resistance.

|Apr 05, 2024
Discovery of low-molecular-weight phenylalanine derivatives as novel HIV capsid modulators with improved antiretroviral activity and metabolic stability.

Xiangyi Jiang, Zhen Gao, Prem Prakash Sharma

|Oct 20, 2023
Identification of novel 1,2,3-triazole isatin derivatives as potent SARS-CoV-2 3CLpro inhibitors via click-chemistry-based rapid screening.

Xiangyi Jiang, Jing Li, Antonio Viayna

|Jul 24, 2023
Design, synthesis, and mechanistic study of 2-piperazineone-bearing peptidomimetics as novel HIV capsid modulators.

Xujie Zhang, Lin Sun, Shujing Xu

|Apr 29, 2023
Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors.

Xiangyi Jiang, Boshi Huang, Shawn Rumrill

|Aug 10, 2022
Discovery of novel 1,2,4-triazole phenylalanine derivatives targeting an unexplored region within the interprotomer pocket of the HIV capsid protein.

Xiangyi Jiang, Prem Prakash Sharma, Brijesh Rathi

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Frequent Collaborators

3 joint publications

Xinyong Liu

2 joint publications

Dongwei Kang

2 joint publications

Erik De Clercq

2 joint publications

Peng Zhan