Jeffrey W Johannes

17PUBLICATIONS
112CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targetsPharmacogenomicsFree radical chemistryTransition metal chemistry
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (17)

|Sep 03, 2025
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome.

Avipsa Ghosh, Afshan Ahmed, Konstantina Amoiradaki

|Dec 10, 2024
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor.

Jeffrey W Johannes, Amber Y S Balazs, Derek Barratt

|Feb 27, 2024
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation.

Emily C Erickson, Inchul You, Grace Perry

|Nov 15, 2023
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1.

Anna D Staniszewska, Domenic Pilger, Sonja J Gill

|May 19, 2023
Halide Noninnocence and Direct Photoreduction of Ni(II) Enables Coupling of Aryl Chlorides in Dual Catalytic, Carbon-Heteroatom Bond-Forming Reactions.

Cameron H Chrisman, Max Kudisch, Katherine O Puffer

|Aug 05, 2022
Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper.

Giuditta Illuzzi, Anna D Staniszewska, Sonja J Gill

Pageof 3

Frequent Collaborators

5 joint publications

Michelle L Lamb

4 joint publications

Avipsa Ghosh

3 joint publications

Sonja J Gill

3 joint publications

Andy Pike