Michelle L Lamb

15PUBLICATIONS
60CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targetsBiomolecular modelling and designBiologically active moleculesProteomics and intermolecular interactions (excl. medical proteomics)
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Publications (15)

|Sep 03, 2025
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome.

Avipsa Ghosh, Afshan Ahmed, Konstantina Amoiradaki

|Sep 18, 2024
Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors.

Simon C C Lucas, J Henry Blackwell, Ulf Börjesson

|Aug 12, 2024
Accelerated Discovery of Carbamate Cbl-b Inhibitors Using Generative AI Models and Structure-Based Drug Design.

Taylor R Quinn, Kathryn A Giblin, Clare Thomson

|Jun 25, 2024
Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1.

Simon C C Lucas, Alexander G Milbradt, J Henry Blackwell

|Jun 19, 2024
Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library Screen.

Simon C C Lucas, J Henry Blackwell, Ulf Börjesson

|Jan 16, 2024
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors.

Adelphe M Mfuh, Jeffrey A Boerth, Gayathri Bommakanti

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