Neil P Grimster

10PUBLICATIONS
37CO-AUTHORS
Evolutionary computationMolecular targetsCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designBiologically active molecules
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Journal

Publications (10)

|Jul 21, 2026
Generative AI-Assisted Discovery of HPK1 Inhibitors.

|Jun 16, 2025
Synthetic chemistry enabling the discovery and development of a series of pyrazoles as HPK1 inhibitors.

Anthony J Metrano, Lucas A Morrill, Gayathri Bommakanti

|Feb 10, 2025
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor.

Jason D Shields, David Baker, Amber Y S Balazs

|Aug 12, 2024
Accelerated Discovery of Carbamate Cbl-b Inhibitors Using Generative AI Models and Structure-Based Drug Design.

Taylor R Quinn, Kathryn A Giblin, Clare Thomson

|Jan 16, 2024
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors.

Adelphe M Mfuh, Jeffrey A Boerth, Gayathri Bommakanti

|Dec 20, 2023
Discovery of a Novel Benzodiazepine Series of Cbl-b Inhibitors for the Enhancement of Antitumor Immunity.

Jeffrey A Boerth, Alex J Chinn, Marianne Schimpl

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Frequent Collaborators

6 joint publications

Marianne Schimpl

4 joint publications

Jason G Kettle

3 joint publications

Niresh Hariparsad

3 joint publications

Jason D Shields