Jason G Kettle

20PUBLICATIONS
96CO-AUTHORS
Evolutionary computationMolecular targetsElectrochemical energy storage and conversionBiomolecular modelling and designCheminformatics and quantitative structure-activity relationships
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Publications (20)

|Jul 21, 2026
Generative AI-Assisted Discovery of HPK1 Inhibitors.

|Jun 16, 2026
Discovery of CNS Penetrant SOS1 Inhibitors for the Treatment of KRAS-Dependent Cancers.

|Oct 15, 2025
Focused Structure-Based Virtual Screening Identifies Novel Inhibitors of SOS1.

Silvia Bonomo, Floriane Gibault, Sharan K Bagal

|Feb 10, 2025
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor.

Jason D Shields, David Baker, Amber Y S Balazs

|Jan 27, 2025
Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations.

William McCoull, Clare Thomson, Erin Braybrooke

|Jun 25, 2024
Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1.

Simon C C Lucas, Alexander G Milbradt, J Henry Blackwell

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Frequent Collaborators

6 joint publications

Frederick W Goldberg

5 joint publications

Michael S Bodnarchuk

4 joint publications

Hilary Lewis

4 joint publications

Neil P Grimster