Frederick W Goldberg

12PUBLICATIONS
60CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targetsWastewater treatment processesOrganometallic chemistryBiologically active molecules
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Publications (12)

|Sep 03, 2025
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome.

Avipsa Ghosh, Afshan Ahmed, Konstantina Amoiradaki

|Feb 10, 2025
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor.

Jason D Shields, David Baker, Amber Y S Balazs

|May 13, 2024
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTAC.

Thomas G Hayhow, Beth Williamson, Mandy Lawson

|Nov 20, 2023
α-Functionalisation of Cyclic Sulfides Enabled by Lithiation Trapping.

Nico Seling, Masakazu Atobe, Kevin Kasten

|Jul 03, 2023
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS<sup>G12C</sup> with Demonstrable CNS Penetration.

Jason G Kettle, Sharan K Bagal, Derek Barratt

|Jan 05, 2023
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit.

Aarti Kawatkar, Roger A Clark, Lorna Hopcroft

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