M Raymond V Finlay

9PUBLICATIONS
43CO-AUTHORS
Biologically active moleculesBiomolecular modelling and designApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Molecular targetsCheminformatics and quantitative structure-activity relationships
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Journal

Publications (9)

|Nov 22, 2024
Discovery of (2R,4R)-4-((S)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.

Scott N Mlynarski, Brian M Aquila, Susan Cantin

|Nov 14, 2024
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.

Jason D Shields, Brian M Aquila, David Emmons

|Mar 13, 2023
Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners.

Aatman S Doshi, Susan Cantin, Marylens Hernandez

|Aug 18, 2022
Optimization of hERG and Pharmacokinetic Properties for Basic Dihydro-8H-purin-8-one Inhibitors of DNA-PK.

Frederick W Goldberg, Attilla K T Ting, David Beattie

|Sep 07, 2021
Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance.

M Raymond V Finlay, Peter Barton, Sue Bickerton

|Dec 19, 2019
The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) Inhibitor.

Frederick W Goldberg, M Raymond V Finlay, Attilla K T Ting

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Frequent Collaborators

3 joint publications

Scott N Mlynarski

3 joint publications

Sharon Tentarelli

2 joint publications

J Willem M Nissink

2 joint publications

Peter D Smith