Sharon Tentarelli

7PUBLICATIONS
45CO-AUTHORS
Biologically active moleculesBiomolecular modelling and designCheminformatics and quantitative structure-activity relationshipsApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Organic chemical synthesis
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Journal

Publications (7)

|Nov 22, 2024
Discovery of (2R,4R)-4-((S)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.

Scott N Mlynarski, Brian M Aquila, Susan Cantin

|Nov 14, 2024
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.

Jason D Shields, Brian M Aquila, David Emmons

|Sep 28, 2024
Optimization of Potent, Efficacious, Selective and Blood-Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations.

Clare Thomson, Erin Braybrooke, Nicola Colclough

|Mar 11, 2024
Development of a Series of Pyrrolopyridone MAT2A Inhibitors.

Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou

|Mar 13, 2023
Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners.

Aatman S Doshi, Susan Cantin, Marylens Hernandez

|Jan 18, 2023
Photocatalyzed Decarboxylative Addition of N-Substituted Acetic Acids to Aldehydes.

Bo Jin, Ariamala Gopalsamy, Bo Peng

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Frequent Collaborators

3 joint publications

M Raymond V Finlay

3 joint publications

Scott N Mlynarski

2 joint publications

William McCoull

2 joint publications

Marianne Schimpl