Alwin G Schuller

6PUBLICATIONS
95CO-AUTHORS
Molecular targetsBiologically active moleculesApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Haematological tumours
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Publications (6)

|Feb 10, 2025
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor.

Jason D Shields, David Baker, Amber Y S Balazs

|Nov 22, 2024
Discovery of (2<i>R</i>,4<i>R</i>)-4-((<i>S</i>)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.

Scott N Mlynarski, Brian M Aquila, Susan Cantin

|Mar 13, 2023
Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners.

Aatman S Doshi, Susan Cantin, Marylens Hernandez

|Mar 08, 2023
Pharmacokinetic/Pharmacodynamic Analysis of Savolitinib plus Osimertinib in an EGFR Mutation-Positive, MET-Amplified Non-Small Cell Lung Cancer Model.

Rhys D O Jones, Klas Petersson, Areya Tabatabai

|Sep 13, 2021
Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of <i>EGFR</i>-mutant lung cancer.

Pınar Özden Eser, Raymond M Paranal, Jieun Son

|Jan 26, 2021
Design and optimisation of dendrimer-conjugated Bcl-2/x<sub>L</sub> inhibitor, AZD0466, with improved therapeutic index for cancer therapy.

Claire M Patterson, Srividya B Balachander, Iain Grant

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Frequent Collaborators

2 joint publications

M Raymond V Finlay

2 joint publications

Scott N Mlynarski

2 joint publications

Sonya Gales

2 joint publications

Sharon Tentarelli