William McCoull

17PUBLICATIONS
71CO-AUTHORS
Molecular targetsBiomolecular modelling and designElectrochemical energy storage and conversionCheminformatics and quantitative structure-activity relationshipsApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)
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Publications (17)

|Feb 02, 2026
Preclinical to Clinical Translation of Pharmacokinetic-Pharmacodynamic Relationship in EGFR Exon20Ins Mutations: A Modeling Framework for Irreversible Inhibitors.

Adriana Savoca, Diana Zindel, Radoslaw Polanski

|Jul 07, 2025
The changing landscape of medicinal chemistry optimization.

Anita Rácz, Levente M Mihalovits, Maximilian Beckers

|Jan 27, 2025
Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations.

William McCoull, Clare Thomson, Erin Braybrooke

|Sep 28, 2024
Optimization of Potent, Efficacious, Selective and Blood-Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations.

Clare Thomson, Erin Braybrooke, Nicola Colclough

|May 21, 2024
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.

Clare Thomson, Peter Barton, Erin Braybrooke

|May 09, 2022
Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems.

Beth Williamson, Lindsay McMurray, Scott Boyd

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Frequent Collaborators

4 joint publications

Clare Thomson

3 joint publications

Andrew D Ferguson

3 joint publications

Richard A Ward

3 joint publications

J Willem M Nissink