J Willem M Nissink

16PUBLICATIONS
54CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsElectrochemical energy storage and conversionWastewater treatment processesBiologically active moleculesSemi- and unsupervised learning
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Publications (16)

|Sep 17, 2025
Fragment-Based Discovery and Structure-Led Optimization of MSC778, the First Potent, Selective, and Orally Bioavailable FEN1 Inhibitor.

Sam E Mann, Julien Lefranc, Omar Alkhatib

|Jan 27, 2025
Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations.

William McCoull, Clare Thomson, Erin Braybrooke

|May 13, 2024
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTAC.

Thomas G Hayhow, Beth Williamson, Mandy Lawson

|Jun 21, 2023
Correction to "Discovery of a Thiadiazole-Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models".

M Raymond V Finlay, Mark Anderton, Andrew Bailey

|Apr 18, 2023
Does a Machine-Learned Potential Perform Better Than an Optimally Tuned Traditional Force Field? A Case Study on Fluorohydrins.

João Morado, Paul N Mortenson, J Willem M Nissink

|Feb 02, 2023
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists.

James S Scott, Darren Stead, Bernard Barlaam

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Frequent Collaborators

3 joint publications

William McCoull

3 joint publications

Rodrigo J Carbajo

2 joint publications

João Morado

2 joint publications

Paul N Mortenson