Bernard Barlaam

13PUBLICATIONS
49CO-AUTHORS
Gene and molecular therapyBiologically active moleculesBiomolecular modelling and designCheminformatics and quantitative structure-activity relationshipsMolecular targets
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Publications (13)

|May 22, 2026
Use of Human Dose Prediction Metrics to Enable Discovery of AZD3470, an MTA-Cooperative PRMT5 Inhibitor in Clinical Evaluation.

|Jan 14, 2026
Discovery and Characterization of Diverse Non-nucleotide Inhibitors of DNPH1 Using an Integrated Hit Finding Strategy.

Benjamin C Whitehurst, Niall A Anderson, Argyrides Argyrou

|Nov 06, 2025
Discovery and Optimization of a Non-Nucleoside-Based Series of Inhibitors of 2'-Deoxynucleoside 5'-Monophosphate Glycosidase (DNPH1).

Bernard Barlaam, Luz Alonso-Crisostomo, Niall A Anderson

|Nov 03, 2025
Use of Direct-to-Biology Strategies for the Discovery of 2'-Deoxynucleoside 5'-Monophosphate N-Glycosidase (DNPH1) PROTACs.

Niall A Anderson, Bernard Barlaam, Argyrides Argyrou

|Sep 03, 2025
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome.

Avipsa Ghosh, Afshan Ahmed, Konstantina Amoiradaki

|Jul 31, 2024
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.

James M Smith, Bernard Barlaam, David Beattie

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Frequent Collaborators

4 joint publications

Gavin W Collie

4 joint publications

Michelle L Lamb

4 joint publications

Bin Yang

3 joint publications

Kurt G Pike