Kurt G Pike

5PUBLICATIONS
15CO-AUTHORS
Molecular targetsMolecular medicineBiologically active molecules
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Journal

Publications (5)

|Feb 02, 2024
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390.

Kurt G Pike, Thomas A Hunt, Bernard Barlaam

|Nov 22, 2021
Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase.

Sharan K Bagal, Clare Gregson, Daniel H O' Donovan

|Dec 11, 2020
Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies.

Bernard Barlaam, Robert Casella, Justin Cidado

|Sep 20, 2019
Pharmacology of the ATM Inhibitor AZD0156: Potentiation of Irradiation and Olaparib Responses Preclinically.

Lucy C Riches, Antonio G Trinidad, Gareth Hughes

|Apr 24, 2018
The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2 H-pyran-4-yl)-1,3-dihydro-2 H-imidazo[4,5- c]quinolin-2-one).

Kurt G Pike, Bernard Barlaam, Elaine Cadogan

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Frequent Collaborators

3 joint publications

Bernard Barlaam

2 joint publications

Gareth Hughes

1 joint publications

Gilles Ouvry

1 joint publications

Andrew G Thomason