James Smith

4PUBLICATIONS
19CO-AUTHORS
Gene and molecular therapyMolecular targetsCheminformatics and quantitative structure-activity relationships
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (4)

|May 22, 2026
Use of Human Dose Prediction Metrics to Enable Discovery of AZD3470, an MTA-Cooperative PRMT5 Inhibitor in Clinical Evaluation.

|Jul 31, 2024
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.

James M Smith, Bernard Barlaam, David Beattie

|Mar 11, 2024
Development of a Series of Pyrrolopyridone MAT2A Inhibitors.

Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou

|Apr 26, 2021
Fragment-Based Design of a Potent MAT2a Inhibitor and in Vivo Evaluation in an MTAP Null Xenograft Model.

Claudia De Fusco, Marianne Schimpl, Ulf Börjesson

Pageof 1

Frequent Collaborators

4 joint publications

Graeme Robb

3 joint publications

James S Scott

2 joint publications

Claudia De Fusco

2 joint publications

Marianne Schimpl