Sophie L Cooke

4PUBLICATIONS
39CO-AUTHORS
Gene and molecular therapyMolecular targetsEpigenetics (incl. genome methylation and epigenomics)Genome structure and regulation
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Publications (4)

|May 22, 2026
Use of Human Dose Prediction Metrics to Enable Discovery of AZD3470, an MTA-Cooperative PRMT5 Inhibitor in Clinical Evaluation.

|Jul 31, 2024
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.

James M Smith, Bernard Barlaam, David Beattie

|Nov 05, 2022
Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy.

Laura J Grange, John J Reynolds, Farid Ullah

|Jul 25, 2019
Gcn5 and Rpd3 have a limited role in the regulation of cell cycle transcripts during the G1 and S phases in Saccharomyces cerevisiae.

A Kishkevich, S L Cooke, M R A Harris

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Frequent Collaborators

2 joint publications

Graeme R Robb

2 joint publications

Judit É Debreczeni

2 joint publications

Bernard Barlaam

2 joint publications

James M Smith