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Shaun M Fillery

7PUBLICATIONS

19CO-AUTHORS

Molecular targetsMolecular medicineCharacterisation of biological macromoleculesBiomolecular modelling and designOrganometallic chemistry

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Publications (7)

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|Jul 03, 2023

Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS<sup>G12C</sup> with Demonstrable CNS Penetration.

Jason G Kettle, Sharan K Bagal, Derek Barratt

|Apr 26, 2022

Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS<sup>G12C</sup>.

Jason G Kettle, Sharan K Bagal, Sue Bickerton

|Feb 08, 2022

Discovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models.

Jon J Winter-Holt, Catherine Bardelle, Elisabetta Chiarparin

|Nov 22, 2021

Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase.

Sharan K Bagal, Clare Gregson, Daniel H O' Donovan

|Jul 25, 2020

A Buchwald-Hartwig Protocol to Enable Rapid Linker Exploration of Cereblon E3-Ligase PROTACs*.

Thomas G Hayhow, Rachel E A Borrows, Coura R Diène

|Feb 06, 2020

Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRAS<sup>G12C</sup>.

Jason G Kettle, Sharan K Bagal, Sue Bickerton

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Frequent Collaborators

3 joint publications

Jason G Kettle

3 joint publications

Michael S Bodnarchuk

3 joint publications

Frederick W Goldberg

3 joint publications

Graeme Robb

2 joint publications

Doyle J Cassar

2 joint publications

Hilary J Lewis

1 joint publications

Rodrigo J Carbajo

1 joint publications

Miguel A Cortés González

1 joint publications

Magnus Schou

1 joint publications

Thomas G Hayhow

Frequent Collaborators

3 joint publications

Jason G Kettle

3 joint publications

Michael S Bodnarchuk

3 joint publications

Frederick W Goldberg

3 joint publications

Graeme Robb

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