Hilary Lewis
9PUBLICATIONS
98CO-AUTHORS
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Publications (9)
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|Feb 02, 2026
Preclinical to Clinical Translation of Pharmacokinetic-Pharmacodynamic Relationship in EGFR Exon20Ins Mutations: A Modeling Framework for Irreversible Inhibitors.Adriana Savoca, Diana Zindel, Radoslaw Polanski
|May 13, 2024
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTAC.Thomas G Hayhow, Beth Williamson, Mandy Lawson
|Sep 19, 2023
The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance.Mandy Lawson, Natalie Cureton, Susana Ros
|Jul 03, 2023
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration.Jason G Kettle, Sharan K Bagal, Derek Barratt
|Aug 05, 2022
AZD4625 is a Potent and Selective Inhibitor of KRASG12C.Atanu Chakraborty, Lyndsey Hanson, David Robinson
|Jul 26, 2022
Accelerating the Validation of Endogenous On-Target Engagement and In Cellulo Kinetic Assessment for Covalent Inhibitors of KRASG12C in Early Drug Discovery.Vasudev Kantae, Radoslaw Polanski, Hilary J Lewis
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Frequent Collaborators
4 joint publications
Jason G Kettle
3 joint publications
Michael S Bodnarchuk
3 joint publications
Radoslaw Polanski
3 joint publications
Frederick W Goldberg
2 joint publications
Aaron Smith
2 joint publications
David I Fisher
2 joint publications
Graeme Robb
2 joint publications
Rodrigo J Carbajo
2 joint publications
Doyle J Cassar
2 joint publications
Shaun Fillery
