Jason D Shields

5PUBLICATIONS
25CO-AUTHORS
Evolutionary computationMolecular targetsBiomolecular modelling and designInorganic green chemistry
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Publications (5)

|Jul 21, 2026
Generative AI-Assisted Discovery of HPK1 Inhibitors.

|Jun 16, 2025
Synthetic chemistry enabling the discovery and development of a series of pyrazoles as HPK1 inhibitors.

Anthony J Metrano, Lucas A Morrill, Gayathri Bommakanti

|Feb 10, 2025
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor.

Jason D Shields, David Baker, Amber Y S Balazs

|Nov 14, 2024
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.

Jason D Shields, Brian M Aquila, David Emmons

|Apr 26, 2024
AiZynth impact on medicinal chemistry practice at AstraZeneca.

Jason D Shields, Rachel Howells, Gillian Lamont

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Frequent Collaborators

3 joint publications

Marianne Schimpl

3 joint publications

Robert E Ziegler

3 joint publications

Neil P Grimster

2 joint publications

Rachel Howells